The Company was established as Jomaa Pharma GmbH in 2003 following the acquisition of Jomaa Pharmaka GmbH by BioAgency AG. Jomaa Pharmaka GmbH had been founded five years previously by Hassan Jomaa and Ewald Beck as an extension of their academic posts at the University of Giessen for the purpose of attracting venture capital to support innovative drug discovery primarily in the field of infectious disease.

Following its dissociation from BioAgency AG in 2013, Jomaa Pharma GmbH became a privately owned company, financed by corporate and individual investors. It is structured as a German/UK alliance with offices in Hamburg and Westerham respectively, and changed its name into DMG Deutsche Malaria GmbH in November 2017.